All immunoassays, regardless of manufacturer, can be affected by interfering substances. The prevalence of immunoassay interference is variable and depends on the type of interferent present. Some common interferences include icterus, hemolysis, lipemia, human anti-mouse antibodies (HAMA), and biotin. Biotin interference was the topic of a recent FDA safety alert,* which highlights the need for clinicians to be aware of laboratory results that may be affected by a variety of interfering substances.
Biotin has gained increasing popularity as an over-the-counter supplement and is commonly included in multivitamins and beauty products marketed for hair and nails.
Download the FAQ to learn:
- How might immunoassays be affected?
- What do clinicians and laboratorians need to know about biotin?
- How is Siemens Healthineers managing the risk of biotin interference?
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