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MAGNETOM Cima.X Tractography Three-Plane

MR NeurologyUnderstanding complexity

MRI is the ultimate tool for diagnostic imaging and neuroscience research, providing morphological images with the highest spatial resolution and unmatched soft tissue contrast as well as unique functional information of the central nervous system (CNS).

The advent of new powerful gradient systems has opened opportunities to explore the microstructure of the brain at an unprecedented level. Deep learning reconstruction is fundamentally transforming MR imaging and will allow higher patient throughput without compromising image quality. 

At Siemens Healthineers, we firmly believe that combining the latest hardware innovations with software-based features such as deep learning reconstruction will create great momentum in the neuroradiological and neuroscience community. Let's continue to explore the human brain, together.

Highlights

Be at the forefront of the neuroimaging community with our comprehensive solution portfolio for diagnostic imaging and neuroscience research.

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Deep Resolve 01
MAGNETOM Cima.X 01
MAGNETOM Terra.X01
Deep Resolve

Deep Resolve 

At the forefront of the revolution in MRI acceleration, Deep Resolve enables game-changing acceleration by combining parallel imaging, SMS and AI-powered image reconstruction1.

Your benefits:

  • Drastically reduce scan times and double your in-plane resolution
  • Unlock b-values that were previously difficult to obtain in diffusion-weighted imaging
  • Open a new dimension in speed with planned Deep Resolve 3D*
Deep Resolve
MAGNETOM Cima.X
MAGNETOM Terra.X
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Clinical Applications

Siemens Healthineers exclusive applications

At Siemens Healthineers MR, we are driven to deliver outstanding applications that shift the limits of MRI. The following exclusive features can only be found on our MRI machines and set you apart from competition.


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Deep Resolve Swift Brain01
Simultaneous Multi-Slice01
BioMatrix Motion Sensor401
Wave-CAIPI SWI01
MR Fingerprinting01
BioMatrix Head/Neck 6401
myExam Assist for Brain and Spine01
Deep Resolve Swift Brain

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Deep Resolve Swift Brain

Based on a multi-shot EPI approach, sophisticated magnetization preparation and deep learning reconstruction, Deep Resolve Swift Brain enables the fastest brain examination ever on our MRI machines. Together with Simultaneous Multi-Slice, net scan times below 2:00 minutes are possible.

Your benefits:

  • Fastest standard brain exam on our MRI scanners by multi-shot EPI and deep learning reconstruction
  • A new Static Field Correction will further reduce geometric distortions
  • Full flexibility: Only acquire contrasts required for your clinical question, save even more scan time
Deep Resolve Swift Brain
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magnetic resonance fingerprinting
Cima.X Head SWI Wave-CAIPI HighRes
MR Fingerprinting (MRF)
BioMatrix Head Neck 64
myExam Brain Assist SHUI
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More neurology applications 

Address all relevant clinical questions with our rich portfolio of MR neurology applications.

Magnetic Resonance Imaging - Application - ZOOMit

ZOOMit

ZOOMit – the first TimTX TrueShape application for clinical use – uses dynamic excitation pulses to achieve selective field-of-view (zoomed) imaging. Zoom into your image to appreciate the smallest details, improve diagnostics and expand research possibilities with ZOOMit, powered by TimTX TrueShape.

Your benefits:

  • Zoomed imaging for EPI (DWI and BOLD) and SPACE
  • Reduced susceptibility artifacts and geometric distortions in challenging anatomies
  • Higher temporal resolution through faster imaging


Magnetic Resonance Imaging - Application - ASL (Arterial Spin Labeling)

ASL (Arterial Spin Labeling)

ASL is an MR technique using the water in arterial blood as an endogenous contrast agent to evaluate perfusion non-invasively. Pseudo-continuous ASL (PCASL) allows larger coverage with more and thinner slices in a shorter acquisition time, resulting in higher perfusion image quality.

Your benefits:

  • 2D and 3D PCASL enable higher in-plane resolution and thinner slices
  • Automatic generation of relative CBF and Bolus Arrival Time maps
  • M0 maps are available for research purposes


Cima.X Fit Head SWI Wave-CAIPI

SWI (Susceptibility-Weighted Imaging) 

SWI is an MRI contrast which exploits the susceptibility differences between tissues. As a result SWI can detect deoxygenated blood, products of blood decomposition and microscopic iron deposits much better than conventional MR techniques.

Your benefits:

  • Improved depiction compared to T2* contrast of susceptibility variations such as hemorrhages and microbleeding
  • 3D imaging for complete brain coverage
  • The perfect CAIPIRINHA: Wave-CAIPI SWI for maximum acceleration in SWI


BLADE Diffusion

HASTE and BLADE diffusion

HASTE and BLADE diffusion enable virtually distortion-free diffusion-weighted imaging (DWI) by employing non-EPI acquisition methods. These methods have been found helpful for the detection of cholesteatoma7-9 and bring clarity to DWI in challenging anatomies where susceptibility artifacts cannot be avoided10.

Your benefits:

  • Non-EPI-based DWI that is virtually free of geometric distortion
  • Siemens Healthineers exclusive: SMS capability for BLADE diffusion to keep scan times at bay
  • Superb detection of difficult pathologies such as cholesteatoma7-9 and cerebellopontine angle tumors10


Clinical Focus Topics 

mri-Headache

Headache 

In clinical routine, many MRI scans deal with unspecified headache disorders that account for 50% of all neurology related disorders11. MRI is a tool to clarify if abnormalities in the brain are responsible for the symptoms, but 90% of these scans are usually without pathological findings12. So there is a large amount of routine brain MRI scans that require fast and robust technology to deliver reliable results. We have what it takes to address these requirements:

Emergencies

Emergencies 

Stroke is the second leading cause for death among all diseases, only surpassed by cardiovascular disease11. Time is brain in acute stroke, and while CT is typically the method of choice, MRI is considered equivalent by current guidelines13 and has even been shown to be more effective14. Besides stroke and in particular wake-up strokes15, MRI can play a decisive role in vulnerable groups such as pregnant women and cranial trauma16. We support these use cases with innovations such as 

Neurodegenerative Diseases

Neurodegenerative Diseases 

Neurodegenerative Diseases (ND) such as Alzheimer’s Disease (AD), dementia, or Multiple Sclerosis (MS) have seen a significant increase in prevalence over the last decade and are the second leading cause of death among neurology related disease, only surpassed by stroke11. With ageing populations in many developed countries, increasing numbers of ND are expected. MRI plays a major role in diagnosing and monitoring diseases such as MS. Additionally, it is also mandated for therapy monitoring of the newest generation of AD drugs that slow the progress of early stage AD. 

Clinical Practice

Siemens Healthineers‘ global MRI community MAGNETOM World offers peer-to-peer information, providing first-hand experiences from MAGNETOM users.

Case Studies

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Deep Resolve Boost and Sharp for SPACE and VIBE sequences as well as SMS BLADE are still under development and not commercially available. Their future availability cannot be ensured. 
1
Applies to Deep Resolve Boost and Sharp
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≥ 200 mT/m (±3% for design tolerances) 
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Open Recon is to add clinical reconstructions to the system, if signed and released for clinical use by SHS. Any other recon used e.g., by researchers is automatically labelled not for diagnostic use, which may require observation of national regulations.
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BioMatrix Motion Sensor is exclusively available for MAGNETOM Cima.X and MAGNETOM Cima.X Fit with syngo MR XA61A.
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M. Lang et al.: Clinical Evaluation of Scout Accelerated Motion Estimation and Reduction Technique for 3D MR Imaging in the Inpatient and Emergency Department Settings. AJNR Am J Neuroradiol 44:125–33 (2023)
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D. Polak et al.: Scout accelerated motion estimation and reduction (SAMER). Magn Reson Med 87:163-178 (2022)
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De Foer B. et al: The value of single-shot turbo spin-echo diffusion-weighted MR imaging in the detection of middle ear cholesteatoma. Neuroradiology 49:841-848 (2007)
8
Fan X. et al.: The value of turbo spin-echo diffusion-weighted imaging apparent diffusion coefficient in the diagnosis of temporal bone cholesteatoma; Clin Radiol 74:977.e1-977.e7 (2019)
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Henninger B. and Kremser C.: Diffusion weighted imaging for the detection and evaluation of cholesteatoma; World J Radiol 9:217-222 (2017)
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Fu Q. et al.: Clinical comparison of single-shot EPI, readout-segmented EPI and TGSE-BLADE for diffusion-weighted imaging of cerebellopontine angle tumors on 3 tesla. Magn Reson Imaging 84:76-83 (2021)
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Global Burden of Disease Collaborative Network. Global Burden of Disease Study 2019 (GBD 2019) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2020.
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 R.W. Evans: Incidental Findings and Normal Anatomical Variants on MRI of the Brain in Adults for Primary Headaches; Headache 57:780-192 (2017)
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W.J. Powers et al.: Guidelines for the Early Management of Patients With Acute Ischemic Stroke; Stroke 50:e344-e418 (2019).
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J.A. Chalela et al.: Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison; Lancet 369:293-298 (2007)
15
G. Thomalla et al.: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset; N Engl J Med 379:611-622 (2018).
16
A. Schweitzer et al.: Traumatic Brain Injury: Imaging Patterns and Complications; RadioGraphics 39:1571—1595 (2019).