![Screenshot of Determination of sex-specific 99th percentile upper reference limits for a point of care high sensitivity cardiac troponin I assay](https://marketing.webassets.siemens-healthineers.com/83fc58eed5dba00d/d76e3fef3a2a/v/e235d63021c7/Fred_Apple_Atellica_VTLi_2021.jpg)
High sensitivity (hs) cardiac troponin (cTn) assays are defined per the IFCC Committee on Clinical Application of Cardiac Biomarker (C-CB) by the ability to measure ≥ 50% of concentrations greater than the limit of detection (LoD) with an impression of ≤10% at sex-specific 99th percentiles. This study determined the sex-specific 99th percentile upper reference limits for males and females utilizing heparinized plasma from AACC universal sample bank for the Siemens point of care (POC) Atellica® VTLi hs-cTnI immunoassay.