Conclusion
50° wide-angle Tomosynthesis 3D imaging opens up a technological window that delineates all the hurdles faced with basic 2D mammography. 50° wide-angle Tomosynthesis benefit from a superior, highly accurate method of cancer detection that allows you to diagnose with confidence. This results in excellent outcomes for breast care professionals, radiologists, and – most importantly – for the many women and their families personally affected by breast cancer. Accordingly in the near future, Tomosynthesis will lead the clinical practice of diagnostic mammography. Early clinical experience has shown tomosynthesis to be uniquely helpful in evaluating IDC.
Introduction
Invasive Ductal Carcinoma (IDC) is the most prevalent type of invasive breast cancer. 2D Digital mammography is the standard technique used for both screening and diagnosis of breast cancer. Unfortunately, it has inherent technical limitations in the form of poor sensitivity because of the tissue overlapping especially in dense breasts or superposition of ordinary mammary parenchyma. Some studies reveal that 2D mammography may leave as many as 30 to 50 percent of malignant tumors undetected.
Scanning technique
All patients have been scanned on the Siemens Healthineers MAMMOMAT Revelation equipped with state-of-the-art 50° Wide-Angle Tomosynthesis 3D imaging. With tomosynthesis, a full-field digital mammography system acquires multiple projection images of the breast. The X-ray tube moves through a 50° arc above the stationary detector, acquiring an image every two degrees for a total of 25 projections. The projection images are then reconstructed into a 3D volume in DICOM format. The MAMMOMAT Revelation automatically compresses according to the patient’s breast characteristics. High Definition Breast Tomosynthesis incorporates with the patented Enhanced Multiple Parameter Iterative Reconstruction (EMPIRE) Technology. The unique combination of iterative and machine learning algorithms reconstructs images with unparalleled clarity in both contrast and detail.
Conclusion
50° wide-angle Tomosynthesis 3D imaging opens up a technological window that delineates all the hurdles faced with basic 2D mammography. 50° wide-angle Tomosynthesis benefit from a superior, highly accurate method of cancer detection that allows you to diagnose with confidence. This results in excellent outcomes for breast care professionals, radiologists, and – most importantly – for the many women and their families personally affected by breast cancer. Accordingly in the near future, Tomosynthesis will lead the clinical practice of diagnostic mammography. Early clinical experience has shown tomosynthesis to be uniquely helpful in evaluating IDC.
Introduction
Invasive Ductal Carcinoma (IDC) is the most prevalent type of invasive breast cancer. 2D Digital mammography is the standard technique used for both screening and diagnosis of breast cancer. Unfortunately, it has inherent technical limitations in the form of poor sensitivity because of the tissue overlapping especially in dense breasts or superposition of ordinary mammary parenchyma. Some studies reveal that 2D mammography may leave as many as 30 to 50 percent of malignant tumors undetected.
Scanning technique
All patients have been scanned on the Siemens Healthineers MAMMOMAT Revelation equipped with state-of-the-art 50° Wide-Angle Tomosynthesis 3D imaging. With tomosynthesis, a full-field digital mammography system acquires multiple projection images of the breast. The X-ray tube moves through a 50° arc above the stationary detector, acquiring an image every two degrees for a total of 25 projections. The projection images are then reconstructed into a 3D volume in DICOM format. The MAMMOMAT Revelation automatically compresses according to the patient’s breast characteristics. High Definition Breast Tomosynthesis incorporates with the patented Enhanced Multiple Parameter Iterative Reconstruction (EMPIRE) Technology. The unique combination of iterative and machine learning algorithms reconstructs images with unparalleled clarity in both contrast and detail.
Conclusion
50° wide-angle Tomosynthesis 3D imaging opens up a technological window that delineates all the hurdles faced with basic 2D mammography. 50° wide-angle Tomosynthesis benefit from a superior, highly accurate method of cancer detection that allows you to diagnose with confidence. This results in excellent outcomes for breast care professionals, radiologists, and – most importantly – for the many women and their families personally affected by breast cancer. Accordingly in the near future, Tomosynthesis will lead the clinical practice of diagnostic mammography. Early clinical experience has shown tomosynthesis to be uniquely helpful in evaluating IDC.
Case Study 1
Fig. 2 - 3D tomosynthesis cuts delineate the lesion precisely and it was nicely seen as a
speculated mass.
Alfa Scan, Cairo, Egypt | Prof. Dr. Naglaa Abd El-Razek
Stereotactic biopsy was done, and the lesion was pathologically diagnosed as Invasive Ductal Carcinoma (IDC) grade 1.
Fig. 1 - 2D mammography shows left breast UIQ architecture distortion in the CC view and
asymmetric density in the MLO.
Alfa Scan, Cairo, Egypt | Prof. Dr. Naglaa Abd El-Razek
40-year-old woman presented for screening. Mammography shows left breast UIQ architecture distortion in the CC view and asymmetric density in the MLO; the lesion was nicely seen as a speculated mass in the 3D tomosynthesis cuts. Hence, this was categorized as BIRADS 5.
Fig. 2 - 3D tomosynthesis cuts delineate the lesion precisely and it was nicely seen as a
speculated mass.
Alfa Scan, Cairo, Egypt | Prof. Dr. Naglaa Abd El-Razek
Stereotactic biopsy was done, and the lesion was pathologically diagnosed as Invasive Ductal Carcinoma (IDC) grade 1.
Fig. 1 - 2D mammography shows left breast UIQ architecture distortion in the CC view and
asymmetric density in the MLO.
Alfa Scan, Cairo, Egypt | Prof. Dr. Naglaa Abd El-Razek
40-year-old woman presented for screening. Mammography shows left breast UIQ architecture distortion in the CC view and asymmetric density in the MLO; the lesion was nicely seen as a speculated mass in the 3D tomosynthesis cuts. Hence, this was categorized as BIRADS 5.
Fig. 2 - 3D tomosynthesis cuts delineate the lesion precisely and it was nicely seen as a
speculated mass.
Alfa Scan, Cairo, Egypt | Prof. Dr. Naglaa Abd El-Razek
Stereotactic biopsy was done, and the lesion was pathologically diagnosed as Invasive Ductal Carcinoma (IDC) grade 1.
Case Study 2
Fig. 5 - Elastography is performed for the same SOL shows Hard tissue on the elastography map and shows infiltration in the surrounding tissue.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
IDC was well depicted in MLO Tomo View.
Fig. 1 - Basic 2D images – High-density breast with no evidence of IDC
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Asymptomatic 39-year-old woman presented for screening. Mammography 2D images didn’t reveal any evidence of a lesion.
Fig. 2 - 50° wide-angle Tomosynthesis 3D images delineate the IDC in 3D frames.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Additional Tomo, CC, and MLO views were performed due to the high-density breast tissues.
Fig. 3 - 50° Two-dimensional image showing hypoechoic SOL with irregular borders of the lesion.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Tomo MLO reveals the distortion in the tissue parenchyma. Subsequently, Ultrasound was performed, and it led to the early diagnosis of Invasive Ductal Carcinoma (IDC) which is sub-centimetric (exactly 7mm).
Fig. 4 - Color doppler/power imaging is used to demonstrate the Feeding vessel.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
50° wide-angle Tomosynthesis guides us to diagnose IDC early in this particular case, especially with dense breasts.
Fig. 5 - Elastography is performed for the same SOL shows Hard tissue on the elastography map and shows infiltration in the surrounding tissue.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
IDC was well depicted in MLO Tomo View.
Fig. 1 - Basic 2D images – High-density breast with no evidence of IDC
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Asymptomatic 39-year-old woman presented for screening. Mammography 2D images didn’t reveal any evidence of a lesion.
Fig. 2 - 50° wide-angle Tomosynthesis 3D images delineate the IDC in 3D frames.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Additional Tomo, CC, and MLO views were performed due to the high-density breast tissues.
Fig. 3 - 50° Two-dimensional image showing hypoechoic SOL with irregular borders of the lesion.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
Tomo MLO reveals the distortion in the tissue parenchyma. Subsequently, Ultrasound was performed, and it led to the early diagnosis of Invasive Ductal Carcinoma (IDC) which is sub-centimetric (exactly 7mm).
Fig. 4 - Color doppler/power imaging is used to demonstrate the Feeding vessel.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
50° wide-angle Tomosynthesis guides us to diagnose IDC early in this particular case, especially with dense breasts.
Fig. 5 - Elastography is performed for the same SOL shows Hard tissue on the elastography map and shows infiltration in the surrounding tissue.
Clemenceau Medical Center, UAE |
Dr. Tatiana Khoury, Breast Imaging Radiologist
Dr. Tatiana Khoury, Breast Imaging Radiologist
IDC was well depicted in MLO Tomo View.
Contact

Prof. Dr. Naglaa Abd El-Razek
Professor of Diagnostic and Interventional Radiology, Cairo University
Alfa Scan, Cairo, Egypt
Contact

Dr. Tatiana Khoury
Breast Imaging Radiologist
Clemenceau Medical Center, UAE
