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Symbia Pro.specta SPECT/CTClinical versatility and theranostics applications

Theranostics Clinical Versatility 16x9 — A sequential xSPECT Quant study following ¹⁷⁷Lu-PSMA therapy reveals high tracer concentration in several bone metastases, with gradual washout.

Unlock the potential of theranostics

The global theranostics market is projected to grow at a rate of 24% through 2029.¹ Unlock the potential of theranostics and beyond with advanced SPECT/CT imaging. Symbia Pro.specta with myExam Companion offers a versatile SPECT detector design, specialized clinical tools, fast, low-dose CT, proven quantification solutions, and the ability to handle all energy levels—making it perfect for your theranostics needs.

See why Symbia Pro.specta stands out as a flexible and adaptable SPECT/CT for daily clinical use.

Achieve optimized SPECT/CT imaging for virtually every clinical indication

With its flexible SPECT detector design, specialized clinical tools, intelligent imaging workflows, and fast, low-dose CT, Symbia Pro.specta with myExam Companion offers the versatility needed to be the singular choice for all your SPECT/CT imaging needs.

See what's possible with Symbia Pro.specta

See what’s possible when you can customize your SPECT/CT scanner with technologies that automatically optimize image quality and workflow for theranostics, cardiology, oncology, neurology, and more.

Symbia Pro.specta Theranostics Clinical Case 3

^{Data and images courtesy of Unithera, Glen Burnie, Maryland, USA.}

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

SPECT
Scan acquisition: 2 bed positions/60 stops per detector; 30 min WB study: 15 seconds per stop; 10 min WB study: 5 seconds per stop; Image reconstruction: 128 x 128 matrix, OSCGMM 24/4s; Injected dose: 177Lu PSMA 197 mCi (7300 MBq)

CT
Scan parameters: 110 kVSn/40 ref mAs 0.8 sec rotation; 32 x 0.7 mm collimation, 5 mm recon

MI Symbia Pro.specta Theranostics Clinical Case 1

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 7 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: Iodine 131 (¹³¹l) 29 mCi (1,100 MBq)

CT
Scan parameters: 130 kV/13 ref mAs

Symbia Pro.specta SPECT/CT with myExam Companion Clinical Images

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

SPECT
Scan acquisition: IQ•SPECT, step-and-shoot method, 22 seconds per stop, 17 stops per detector; Total scan time: 6.2 minutes; Image reconstruction: 128 x 128 matrix, OSCGM, 48i1s, Gaussian filter 10; CT attenuation correction (CTAC); Injected dose: ^99mTc-Myoview (dose amount anonymized)

CT
Scan parameters: 120 kV/56 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

SPECT
Scan acquisition: 60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-HIDA 3.8 mCi (142 MBq)

CT
SAFIRE
Scan parameters: 120 kV/40 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 2-mm recon, BR40 S3 iMAR²

^{Data courtesy of Baylor Scott, White Medical Center, Temple, Texas, USA.}

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

SPECT
Scan acquisition: 1 bed position/48 stops per detector, 25 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-Sestamibi (dose amount anonymized); Post-injection delay: 2 hours

CT
SAFIRE
Scan parameters: 110 kV/90 ref mAs, 0.8-sec rotation, 32 x 0.7-mm collimation, 5-mm recon, Qr40S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

SPECT
Scan acquisition: 2 bed positions/60 stops per detector, 15 seconds per stop; Image reconstruction: 128 x 128 matrix, Flash3D, 18i4s; Injected dose: ¹¹¹In-Octreotide 4.7 mCi (176 MBq); Post-injection delay: 4 and 24 hours

CT
SAFIRE
Scan parameters: 120 kV/213 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

SPECT
Scan acquisition: Low-energy high-resolution (LEHR), step-and-shoot method, 40 seconds per view; Image reconstruction: OSEM3D, 10i8s, Gaussian filter 8; Injected dose: ¹²³I-Ioflupane 4.9 mCi (182.40 MBq)

CT
Scan parameters: 110 kV/24 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 7i15s; Injected dose: ^99mTc-HMDP 20.9 mCi (776 MBq); Post-injection delay: 2 hours

CT
SAFIRE
Scan parameters: 130 kV/30 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

Read the complete clinical case study

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

SPECT
Scan acquisition: 60 stops per detector, 20 seconds per stop; Image reconstruction: 128 x 128 matrix, xSPECT Bone; Injected dose: ^99mTc-HMDP 16.3 mCi (603 MBq); Post-injection delay: 3 hours

CT
SAFIRE
Scan parameters: 120 kV/150 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

SPECT
Scan acquisition: 30 stops per detector, 20 seconds per stop; Image reconstruction: 128 x 128 matrix, xSPECT Bone; Injected dose: ^99mTc-HMDP 15.6 mCi (578 MBq); Post-injection delay: 3 hours

CT
SAFIRE
Scan parameters: 110 kV/181 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

Read the complete clinical case study

^{Data and images courtesy of Unithera, Glen Burnie, Maryland, USA.}

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

CT
Scan parameters: 110 kVSn/40 ref mAs 0.8 sec rotation; 32 x 0.7 mm collimation, 5 mm recon

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

SPECT
Scan acquisition: 3 bed positions/60 stops per detector, 7 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: Iodine 131 (¹³¹l) 29 mCi (1,100 MBq)

CT
Scan parameters: 130 kV/13 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

CT
Scan parameters: 120 kV/56 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

SPECT
Scan acquisition: 60 stops per detector, 10 seconds per stop; Image reconstruction: 128 x 128 matrix, OSEM3D, 24i4s; Injected dose: ^99mTc-HIDA 3.8 mCi (142 MBq)

CT
SAFIRE
Scan parameters: 120 kV/40 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 2-mm recon, BR40 S3 iMAR²

^{Data courtesy of Baylor Scott, White Medical Center, Temple, Texas, USA.}

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

CT
SAFIRE
Scan parameters: 110 kV/90 ref mAs, 0.8-sec rotation, 32 x 0.7-mm collimation, 5-mm recon, Qr40S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

CT
SAFIRE
Scan parameters: 120 kV/213 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

CT
Scan parameters: 110 kV/24 ref mAs

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

CT
SAFIRE
Scan parameters: 130 kV/30 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1.5-mm recon, BR40 S3

Read the complete clinical case study

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

CT
SAFIRE
Scan parameters: 120 kV/150 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

^{Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, UK.}

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

CT
SAFIRE
Scan parameters: 110 kV/181 ref mAs, 0.33-sec rotation, 32 x 0.7-mm collimation, 1-mm recon, BR44 S3 iMAR²

Read the complete clinical case study

Make the most of your everyday

Symbia Pro.specta with myExam Companion combines dedicated clinical tools and intelligent imaging workflows to help you seamlessly transition from one exam to another—with consistent, high-quality results.

Customer voices

Hear from experts about their experiences with Symbia Pro.specta SPECT/CT.

"We decided to go with the Symbia Pro.specta SPECT/CT for our theranostics program because it is so versatile. We are able to do dedicated CT, general nuclear medicine, and SPECT/CT on this. With our clinical trial program, we were missing out on a handful of clinical trials that required dosimetry as part of those protocols. So, when we put this SPECT/CT in, we've been able to implement those protocols here at our practice and offer those to our patients." ⁴

Scott Degenhardt, NMAA, NCS

Director of theranostics and radiology
Nebraska Cancer Specialists
Omaha, Nebraska, USA

“The system is well-designed and has features that save time and are more practical, which can have a huge impact. Using the features on our Symbia Pro.specta, we can now implement treatment assessment and dosimetry more efficiently. We also utilize the system to perform diagnostic studies as well when needed.” ⁴

Veera Athiainen, MD

Oncologist in the Molecular Radiotherapy Unit at The Comprehensive Cancer Center in Helsinki University, Finland

“With Symbia Pro.specta, our goal is to have a one-stop-shop solution where, for example, if a patient comes for a follow-up prostate bone scan, they will also get a contrast-enhanced CT… It has more flexibility in terms of energy window. We can put anything on it.” ⁴

Erin Ross, PhD

Consultant, clinical scientist, and deputy head of nuclear medicine Queen Elizabeth Hospital Birmingham
Birmingham, United Kingdom

Learn more about Symbia Pro.specta with myExam Companion

Whether you're looking to expand your imaging services, add theranostics capabilities, or perform diagnostic CT, Symbia Pro.specta SPECT/CT with myExam Companion delivers the versatility you need.

Visit the product page

Clinical images courtesy of Unithera, Glen Burnie, Maryland, USA, Baylor Scott & White Medical Center, Temple, Texas, USA, Queen Elizabeth Hospital Birmingham, Birmingham, UK, PeaceHealth, Vancouver, Washington, USA.

Data courtesy on file for general imaging clinical images.

Global Theranostics Market Share, Size and Growth Report, BCC Research, August 2024.

iMAR is designed to yield images with a reduced level of metal artifacts compared to conventional reconstruction if the underlying CT data is distorted by metal being present in the scanned object. The exact amount of metal artifact reduction and the corresponding improvement in image quality achievable depends on numerous factors, including composition and size of the metal part within the object, patient size, anatomical location, and clinical practice. It is recommended, to perform iMAR reconstruction in addition to conventional reconstruction.

Optional.

The statements by Siemens Healthineers customers described herein are based on results that were achieved in the customer's unique setting. Because there is no "typical" hospital or laboratory and many variables exist (eg, hospital size, samples mix, case mix, level of IT, and/or automation adoption), there is no guarantee other customers will achieve the same results.

Symbia Pro.specta and its features are not commercially available in all countries. Future availability cannot be guaranteed.

All trademarks are the property of their respective owners.

Symbia Pro.specta SPECT/CTClinical versatility and theranostics applications

Unlock the potential of theranostics

Achieve optimized SPECT/CT imaging for virtually every clinical indication

See what's possible with Symbia Pro.specta

Lung perfusion SPECT/CT shows patchy perfusion in both lobes in a patient with COPD

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

Fast acquisition protocol allows quantitative assessment of disease after ¹⁷⁷Lu-PSMA therapy

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

¹²³I-MIBG SPECT/CT enables delineation of right adrenal pheochromocytoma

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

Lung perfusion SPECT/CT shows patchy perfusion in both lobes in a patient with COPD

10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment

Fast acquisition protocol allows quantitative assessment of disease after ¹⁷⁷Lu-PSMA therapy

Whole-body SPECT/CT in post-surgery thyroid cancer after ablative ¹³¹I therapy demonstrates residual thyroid

¹²³I-MIBG SPECT/CT enables delineation of right adrenal pheochromocytoma

Fast IQ•SPECT cardiac acquisition delineates normal myocardial perfusion at stress and rest

iMAR improves biliary drainage catheter visualization in ^99mTc-HIDA SPECT/CT following liver tumor embolization

Parathyroid adenoma defined on ^99mTc-MIBI SPECT/CT

¹¹¹In-Octreotide 4- and 24-hour planar and SPECT/CT study shows increasing uptake in para-aortic metastases

Bilateral reduction in striatal dopaminergic receptor density defined on SPECT/CT with ratio analysis

Bone SPECT/CT defines site of fracture of vertical spinal stabilization rod at level of L5 vertebral pedicle

xSPECT Bone and CT with iMAR define reactive bony sclerosis in tibial malunion following plate fixation

xSPECT Bone and xSPECT Quant with iMAR CT define loosening of tibial component in right knee arthroplasty

Lung perfusion SPECT/CT shows patchy perfusion in both lobes in a patient with COPD

Make the most of your everyday

Be ready for theranostics

Go beyond general SPECT/CT

Optimize imaging for each patient

Customer voices

Learn more about Symbia Pro.specta with myExam Companion

Symbia Pro.specta SPECT/CTClinical versatility and theranostics applications

Unlock the potential of theranostics

Achieve optimized SPECT/CT imaging for virtually every clinical indication

See what's possible with Symbia Pro.specta

10-minute whole-body SPECT/CT with xSPECT Quant for 177Lu-PSMA therapy response assessment

Make the most of your everyday

Be ready for theranostics

Go beyond general SPECT/CT

Optimize imaging for each patient

Customer voices

Learn more about Symbia Pro.specta with myExam Companion

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10-minute whole-body SPECT/CT with xSPECT Quant for ¹⁷⁷Lu-PSMA therapy response assessment