Case Studies

An elderly woman with history of asbestos exposure and pleural mesothelioma that was treated with left-sided pleurodesis presented with chest pain and respiratory distress. This case demonstrates how Biograph Vision Quadra™ achieves a 5-minute, low-dose, single-bed, whole-body ¹⁸F-FDG PET/CT to help delineate predominantly pericardial involvement in recurrent pleural mesothelioma.

A male in his 70s with high-risk PSMA-avid prostate cancer underwent ¹⁸F-PSMA-1007 PET/CT and ^99mTc-iPSMA SPECT/CT imaging for initial staging. This case provides a comparative analysis of the clinical utility of ^99mTc-iPSMA SPECT/CT imaging as an alternative to ¹⁸F-PSMA-1007 PET/CT imaging for the initial staging of prostate cancer.

An elderly woman with history of ovarian carcinoma underwent PET/CT evaluation. This case demonstrates how Biograph Vision Quadra™ was utilized to achieve a 5-minute, low-dose, single-bed, whole-body ¹⁸F-FDG PET/CT to help delineate peritoneal carcinomatosis in ovarian carcinoma.

An elderly female with history of a primary intestinal neuroendocrine tumor (NET) and suspicion of recurrence was referred for PET/CT staging to evaluate suspected metastases. This case demonstrates how Biograph Vision Quadra™ PET/CT was utilized to achieve fast, low-dose, single-bed, whole-body ¹⁸F-SiFAlin-TATE PET/CT delineation of neuroendocrine tumor metastases.

By reviewing best-practice examples, this case study series illustrates future radiology challenges that Kantonsspital Baden in Switzerland faced with respective approaches Siemens Healthineers identified to overcome them.

This case study explores five pioneering institutions in ASEAN that have partnered with Siemens Healthineers to improve their clinical capabilities.

Across Canada, Siemens Healthineers is partnering with healthcare facilities to improve technology management and enhance the experience for both patients and staff. Find out here how the Value Partnerships provide services beyond technology management and streamline operations to reduce costs.  

A male in his 70s with a history of prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC) underwent routine ⁶⁸Ga-PSMA-11 PET/CT imaging on Biograph mCT Flow™ PET/CT. ⁶⁸Ga-PSMA-11 PET/CT findings confirmed PSMA expression in the metastatic disease, which qualified the patient for ¹⁷⁷Lu-PSMA-617 treatment. The patient received ¹⁷⁷Lu-PSMA-617 therapy followed by fast, multi-bed, quantitative SPECT/CT imaging after each treatment cycle.

Three patients with metastatic prostate cancer underwent sequential, quantitative SPECT/CT on Symbia™ SPECT/CT following a single dose of albumin-bound ¹⁷⁷Lu PSMA-ALB-56. This case series demonstrates the utility of sequential, quantitative SPECT/CT in obtaining accurate time activity curves (TACs) for subsequent dosimetry, which is of key importance for improving therapeutic outcomes while avoiding toxicity.

By using examples, this case study will show how patient experience can be enhanced in radiology.

A 62-year-old female with atypical chest pain and a history of major factors for coronary artery disease (CAD) underwent a ⁸²Rb PET/CT myocardial perfusion study on a Biograph Vision™ PET/CT scanner. This case demonstrates the value of ⁸²Rb myocardial perfusion PET/CT and blood flow estimation in the delineation of multivessel CAD and post-therapy stent occlusion.

An approximately 75-year-old female presenting with a history of bilateral total knee arthroplasty (TKA) and pain in both knees underwent a ^99mTc HMDP bone study on Symbia Pro.specta™ SPECT/CT. This case highlights the clinical utility of xSPECT™ technologies with iterative metal artifact reduction (iMAR) in the detection of TKA prosthetic loosening.

An approximately 70-year-old female with bilateral femoral intramedullary prostheses presenting with severe pain and slight wound discharge underwent a ^99mTc HMPAO-labeled leukocyte study on Symbia Pro.specta™ SPECT/CT. This case demonstrates the value of using SPECT/CT with radiolabeled leukocytes and iterative metal artifact reduction (iMAR) in the evaluation of bony and prosthetic joint pathologies.

Read how Atellica Inventory Manager has brought calm to Labor Blackholm, a private laboratory in Heilbronn, Germany. This success story begins with five fingers and ends with an important side benefit.