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- Symbia Pro.specta SPECT/CT Case Study Review
![Symbia Pro.specta SPECT/CT scan](https://marketing.webassets.siemens-healthineers.com/01ba4e88143afe71/440976c53ce5/v/437c3c5d3d14/siemens-healthineers_mi_symbia_pro_specta_spect_ct_bone_case.png)
Case Study Review
Symbia Pro.specta SPECT/CT
![SPECT CT scan machine - Symbia Pro.specta SPECT/CT](https://marketing.webassets.siemens-healthineers.com/5943f42c30f775b3/07633e2aa02b/v/747d4b4c9a6f/siemens-healthineers_symbia_pro.specta_spect_ct_machine.png)
Case 1
Virtual planar images derived from multibed bone SPECT/CT reveal sacral fracture in breast cancer patient
![Symbia Pro.specta SPECT/CT scan spine](https://marketing.webassets.siemens-healthineers.com/d435e116236316b7/77d8bf482d3c/v/4949b0bd4ee0/siemens-healthineers_mi_symbia-pro-specta-spect-ct-spine.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Case details
- Multibed bone SPECT/CT performed in a symptomatic breast cancer patient for suspicion of metastatic disease
- Virtual planar anterior and posterior images generated from SPECT data
- Study shows increased uptake in right sacroiliac joint suggestive of sacral insufficiency fracture and degenerative changes of right lamina of L5 vertebrae
- Virtual planar images generated from multibed SPECT helps compare with previous planar studies
SPECT – Symbia Pro.specta™
Scan acquisition
3 bed positions/60 stops per detector, 7 seconds per stop
Image reconstruction
128 x 128 matrix, OSEM3D 7i15s
Injected dose
99mTc HMDP1
Post-injection delay: 2 hours
CT
Scan parameters
130 kV/30 ref mAs
0.33 sec rotation
32 x 0.7 mm collimation
1.5 mm recon
BR40 S3
Case 2
99mTc HMDP bone SPECT/CT shows bone remodeling around stem of femoral component of knee arthroplasty
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![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/274a9cea3f5450b4/62c77c637e26/v/5e8de22362c2/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 7 seconds per stop
Image reconstruction
128 x 128 matrix, Flash3D 5i15s
Injected dose
99mTc HMDP2
Post-injection delay: 3 hours
CT
Scan parameters
110 kV/150 eff mAs
0.33 sec rotation
32 x 0.7 mm collimation
1 mm recon
BR44 S3 iMAR
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/630791553837be4a/7b44fe9c4b86/v/dd5f83910d3b/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Case details
- Post-trauma total knee arthroplasty (TKA) with pain on weight-bearing knee
- 99mTc HMDP bone SPECT/CT shows focal hypermetabolism around the junction of the stem and body of the femoral component of TKA suggestive of reactive changes secondary to bone remodeling
- Photopenic area at the tip of the femoral stem corresponds to sclerotic bone reflecting cortical thickening and sclerosis around prosthetis related to fracture union
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/274a9cea3f5450b4/62c77c637e26/v/5e8de22362c2/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 7 seconds per stop
Image reconstruction
128 x 128 matrix, Flash3D 5i15s
Injected dose
99mTc HMDP2
Post-injection delay: 3 hours
CT
Scan parameters
110 kV/150 eff mAs
0.33 sec rotation
32 x 0.7 mm collimation
1 mm recon
BR44 S3 iMAR
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/630791553837be4a/7b44fe9c4b86/v/dd5f83910d3b/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Case details
- Post-trauma total knee arthroplasty (TKA) with pain on weight-bearing knee
- 99mTc HMDP bone SPECT/CT shows focal hypermetabolism around the junction of the stem and body of the femoral component of TKA suggestive of reactive changes secondary to bone remodeling
- Photopenic area at the tip of the femoral stem corresponds to sclerotic bone reflecting cortical thickening and sclerosis around prosthetis related to fracture union
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/274a9cea3f5450b4/62c77c637e26/v/5e8de22362c2/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 7 seconds per stop
Image reconstruction
128 x 128 matrix, Flash3D 5i15s
Injected dose
99mTc HMDP2
Post-injection delay: 3 hours
CT
Scan parameters
110 kV/150 eff mAs
0.33 sec rotation
32 x 0.7 mm collimation
1 mm recon
BR44 S3 iMAR
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/630791553837be4a/7b44fe9c4b86/v/dd5f83910d3b/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg.png)
![Symbia Pro.specta SPECT/CT scan leg](https://marketing.webassets.siemens-healthineers.com/274a9cea3f5450b4/62c77c637e26/v/5e8de22362c2/siemens-healthineers_mi_symbia-pro-specta-spect-ct-leg3.png)
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Case 3
SPECT/CT lymphoscintigraphy identifies axillary and subcutaneous sentinel nodes in a patient with melanoma
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![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/db842cc8cca63c19/f05c26ffa3fa/v/ff7dcea4a52c/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 15 seconds per stop
Image reconstruction
128 x 128 matrix, OSEM3D 24i4s
Injected dose
99mTc Sulfur Colloid2
CT
Scan parameters
120 kV/68 ref mAs
0.33 sec rotation
32 x 0.7 mm collimation
2 mm recon
BR40F/3
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/522e3b428a897840/030c660d24d5/v/3f765de62100/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Case details
- Patient with melanoma in the skin on the lateral aspect left lower chest wall
- SPECT/CT lymphoscintigraphy defines adjacent subcutaneous sentinel lymph node as well as left axillary node also identified as a sentinel node
- Thin-slice CT sharply defines small sentinel nodes and helps accurate localization of both nodes for precise surgical removal
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/db842cc8cca63c19/f05c26ffa3fa/v/ff7dcea4a52c/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 15 seconds per stop
Image reconstruction
128 x 128 matrix, OSEM3D 24i4s
Injected dose
99mTc Sulfur Colloid2
CT
Scan parameters
120 kV/68 ref mAs
0.33 sec rotation
32 x 0.7 mm collimation
2 mm recon
BR40F/3
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/522e3b428a897840/030c660d24d5/v/3f765de62100/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Case details
- Patient with melanoma in the skin on the lateral aspect left lower chest wall
- SPECT/CT lymphoscintigraphy defines adjacent subcutaneous sentinel lymph node as well as left axillary node also identified as a sentinel node
- Thin-slice CT sharply defines small sentinel nodes and helps accurate localization of both nodes for precise surgical removal
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/db842cc8cca63c19/f05c26ffa3fa/v/ff7dcea4a52c/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma3.png)
Data courtesy of Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Scan details
SPECT – Symbia Pro.specta
Scan acquisition
60 stops per detector, 15 seconds per stop
Image reconstruction
128 x 128 matrix, OSEM3D 24i4s
Injected dose
99mTc Sulfur Colloid2
CT
Scan parameters
120 kV/68 ref mAs
0.33 sec rotation
32 x 0.7 mm collimation
2 mm recon
BR40F/3
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/522e3b428a897840/030c660d24d5/v/3f765de62100/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma.png)
![Symbia Pro.specta SPECT/CT scan melanoma](https://marketing.webassets.siemens-healthineers.com/db842cc8cca63c19/f05c26ffa3fa/v/ff7dcea4a52c/siemens-healthineers_mi_symbia-pro-specta-spect-ct-melanoma3.png)
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1
The amount of metal artifact reduction and corresponding improvement in image quality depends on a number of factors including: composition and size of the metal object, patient size, anatomical location and clinical practice. It is recommended to perform reconstruction with iMAR enabled in addition to conventional reconstruction without iMAR.
2
Dose amount anonymized.
Symbia Pro.specta and its features are not commercially available in all countries. Due to regulatory reasons, their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.