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  5. BIOGRAPH One – Shape the new era

BIOGRAPH OneShape the new era

Theranostics and other novel drug therapies make truly targeted treatments possible for the very first time. To realize this potential, an imaging system is needed that shortens patients’ pathways to a precise diagnosis and timely treatment.


Introducing BIOGRAPH One* – the game-changing PET/MR scanner designed to shape a new era for one simplified patient-centric pathway

BIOGRAPH One – our next-generation PET/MR scanner

Benefits

BIOGRAPH One – designed to support one patient-centric pathway
Image courtesy: ZEMODI, Bremen, Germany1

BIOGRAPH One is designed to support one patient-centric pathway to personalized care. By seamlessly integrating PET and MR into one comprehensive exam, it will support clinicians from diagnosis and staging, through a personalized therapy decision to regular therapy assessments to excel precision and support one streamlined approach.

BIOGRAPH One is designed to excel in PET/MR precision to support confident diagnostic decisions. Featuring the Optiso UDR Pro detector with the largest 35 cm axial FOV2 in PET/MR, it is designed to enable comprehensive capture with excellent sensitivity and ultra-fast TOF3 in real time – delivering clear, detailed images.

Deep Resolve designed to make PET/MR exams faster than ever before
Study-ID: 2aaaa3347

Planned with Deep Resolve for accelerated acquisition and improved resolution in 2D and 3D applications4, BIOGRAPH One has the potential to make PET/MR exams faster than ever before. Designed with a powerful 3T magnet at its heart, BIOGRAPH One will deliver unparalleled performance with outstanding homogeneity, a large 55 x 55 x 50 cm³ field of view and robust gradient power.

BIOGRAPH One is designed to make PET/MR patient positioning easier and more efficient so operators can spend more time on patient care. New BioMatrix Contour Coils will enable operators to reduce setup times and minimize exposure to radiation. Starting the exam directly at the scanner will further streamline the workflow.

BIOGRAPH One will simplify the entire PET/MR scanning workflow with myExam Companion: an intuitive interface designed to assist operators with advanced automation features for PET and MR familiar planning. myExam Companion will empower operators of all experience levels with simplicity and consistency, while new acquisition modes will provide a tailored scanning mode for each patient and condition.

BIOGRAPH One is designed to reduce patient slot times by more than 50 % to under 30 minutes5 for standard whole-body exams, including dedicated brain protocols. With up to 5x faster positioning5 and 2x faster acquisition5 – BIOGRAPH One has the potential to establish PET/MR as a standard clinical modality, aligning patient slot times with typical clinical workflows.

BIOGRAPH One – designed to support one patient-centric pathway
Image courtesy: ZEMODI, Bremen, Germany1

BIOGRAPH One is designed to support one patient-centric pathway to personalized care. By seamlessly integrating PET and MR into one comprehensive exam, it will support clinicians from diagnosis and staging, through a personalized therapy decision to regular therapy assessments to excel precision and support one streamlined approach.

Evidence

BIOGRAPH One – designed to transform PET/MR image quality for a new era

Discover the future of personalized imaging with planned BIOGRAPH One, where high PET precision meets powerful MR performance. Equipped with the innovative Optiso UDR Pro PET detector and a state-of-the-art 3T magnet, this system is designed to enhance small lesion detectability and deliver great soft tissue clarity. Designed for precise quantification, ultra-fast time-of-flight3 performance, and high-quality MR imaging, BIOGRAPH One will support a more patient-centric pathway. Shape the new era in PET/MR and explore the possibilities below.

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Diagnosis and staging01
Therapy assessment01
Brain imaging – BIOGRAPH One

Study-ID: 2aaaa3339 | Image courtesy of RIGS Hospital, Copenhagen, Denmark. 

One stop shop multiparametric imaging for investigation of dementia 

63-year-old male patient
Normal brain metabolism

  • Injected dose:  184 MBq i.v.
  • Uptake time:  76 min p.i.
  • Sequences:  T1 VIBE, T1 MPRAGE, FLAIR, DWI, SWI, T2 TSE
  • MR TA:  12:20 min
  • PET TA:  24:00 min6
Brain imaging – BIOGRAPH One
Full body imaging – BIOGRAPH One
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The strength of PET/MR – a quote library 

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Diagnosis and staging02
Therapy assessment02
Optimized patient management02
Prostate cancer – PET/MR imaging

Prostate cancer  | Study-ID: 4aaaa0080 | Image courtesy: ZEMODI, Bremen, Germany1

“PET/MR avoids 83% of unnecessary biopsies”

The Value of 68Ga-PSMA PET/MRI for Classifying Patients with PI-RADS 3 Lesions on Multiparametric MRI: A Prospective Single-Center Study 

Jingyan Shi, et. al.

Prostate cancer – PET/MR imaging
Multiparametric MRI and Amyloid imaging – PET/MR imaging
Lymphoma – PET/MR imaging
Prostate Cancer – PET/MR imaging
Prostate Cancer – PET/MR imaging
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Planned BIOGRAPH One equipped with

Full 3T performanceDeep Resolve

Open Recon architecture7

BioMatrix Technology State-of-the-art PET detector

Largest axial FOV in PET/MR2

Simplified user interface with myExam Companion Innovative WB scanning modes

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    *
    BIOGRAPH One is currently under development and not commercially available. It’s not for sale in the U.S.A. Its future availability cannot be ensured.
    ​1
    Acquired on BIOGRAPH mMR. Images from BIOGRAPH mMR are provided to illustrate typical PET/MR imaging capabilities and are not specific to BIOGRAPH One.
    2
    Compared to other PET/MR systems. Data on file.
    3
    Ultra-fast time of flight (TOF) is defined as less than 275 picoseconds (ps). Data on file.
    4
    In combination with acceleration techniques as e.g. PAT4. Deep Resolve 3D is still under development and not commercially available. Its future availability cannot be ensured.
    5
    Preliminary data based on an internal single measurement. Patient slot time is defined as time in PET/MR exam room. Data on file.
    6
    For testing IQ purposes.
    7
    Open Recon is to add clinical reconstructions to the system, if signed and released for clinical use by Siemens Healthineers. Any other image reconstruction used, e.g., by researchers, is automatically labelled not for diagnostic use, which may require observation of national regulations.
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