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xSPECT QuantReliable SPECT/CT quantification for clinical routine

xSPECT Quant

Conventional SPECT/CT quantification is manual and time intensive - often requiring specialized resources to manage the complexity and potential for error. As a result, quantitative SPECT/CT is rarely used clinically.

The only tool to offer automated, accurate, and reproducible quantification for a range of isotopes, xSPECT Quant™ has paved the way for routine SPECT/CT quantification.

xSPECT Quant uses a 3% National Institute of Standards and Technology (NIST) traceable precision source, which allows you to easily standardize uptake values across different cameras, dose calibrators, and facilities.

Accurate to within 5%1, xSPECT Quant is the industry’s most precise and reproducible SPECT/CT quantitative solution. Available for 99mTc, 123I, 177Lu, 111In, and 131I2 imaging, xSPECT Quant enables clinical SPECT/CT quantification to more precisely detect disease and better manage therapy.

The absolute quantification capabilities of xSPECT Quant are also a basis for theranostics, the unique approach of combining diagnostics and therapy.

What experts say

“Quantitative images are part of almost every study we do. This allows us to obtain more precise information for each patient. With quantitative data, we are starting to detect abnormalities earlier and tailor treatments.”3
John Prior, PhD, MD, FEBNMCentre Hospitalier Universitaire Vaudois (CHUV)Lausanne, Switzerland
John Prior, PhD, MD, FEBNM
Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Switzerland

Insights

Imaging life

Defining the quantitative future of SPECT/CT

Read more about how the Centre Hospitalier Universitaire Vaudois (CHUV) in Lausanne, Switzerland, is using quantitative SPECT/CT imaging as a meaningful tool for determining prompt diagnoses and developing personalized treatment strategies.

To learn more about theranostics visit SPECT/CT Quantification for theranostics

Clinical image gallery

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Isotope 123I
Isotope 123I
123I xSPECT Quant enables standardized quantification for appropriate diagnosis in equivocal motion disorders.
Isotope 123I
Isotope 111In
Isotope 177Lu
Isotope 99mTc
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Case studies

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99mTc01
177Lu01
111In01
123I01
Differentiation of a rib benign lesion from a metastasis using xSPECT Quant

Differentiation of a rib benign lesion from a metastasis using xSPECT Quant

By Mario Jreige, MD; Patrick Omoumi, MD; John O. Prior, MD, PhD; and Marie Nicod Lalonde, MD
Data courtesy of Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Differentiation of a rib benign lesion from a metastasis using xSPECT Quant
Sequential quantitative SPECT/CT following therapeutic administration of 177Lu DOTATATE in a patient with liver metastases from neuroendocrine tumor
Robust quantification of neuroendocrine tumor imaging: xSPECT Quant with 111In tracers enables new possibilities in SPECT/CT imaging
123I xSPECT Quant enables standardized quantification in unclear motion disorder
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White paper

White paper
Data courtesy of Friedrich Alexander University, Erlangen, Germany.

Accurate, reproducible, and standardized quantification

Written by A. Hans Vija, PhD, Carl von Gall, MD, and Partha Ghosh, MD
Siemens Healthineers Molecular Imaging

1
Data on file.
2
xSPECT Quant 131I is not commercially available in all countries. Due to regulatory reasons, its future availability cannot be guaranteed. Please contact your local Siemens organization for further details.
3
The statements by Siemens Healthineers' customers described herein are based on results that were achieved in the customer's unique setting. Since there is no "typical" hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that other customers will achieve the same results.
4
177Lu PSMA is not currently recognized by the U.S. Food and Drug Administration (FDA) or other regulatory agencies as being safe and effective. Siemens does not make any claims regarding its use.