Bone Metabolism

In the past decades, the global incidence of osteoporosis has increased dramatically with rising life expectancy, and over 200 million people suffer from osteoporosis worldwide. By 2050, the global cost of osteoporosis is expected to exceed $130 billion and the annual hip fracture incidence is expected to increase to 6.3 million.^1,2 The highest risk of hip fractures are currently found in Norway, Sweden, Iceland, Denmark, and the United States, but by 2050 Asia is expected to account for almost one-half of all global fractures.^3,4