IQ•SPECT™ delivers fast myocardial perfusion imaging (MPI) with similar diagnostic confidence to low-energy high-resolution (LEHR), but with the advantage of high acquisition speed as well as the possibility of integrated diagnostic CT-based attenuation correction. This white paper briefly explains the technical aspects of IQ•SPECT and demonstrates normal patterns and variations, as well as shows a series of clinical examples of ischemia and infarction to familiarize nuclear cardiologists with IQ•SPECT.