Symbia Intevo BoldMore CT for your SPECT/CT

Symbia Intevo Bold™ combines high-performance CT with advanced SPECT imaging to accommodate even the most challenging situations. For those who want more from their system, Symbia Intevo Bold offers the flexibility to take your capabilities even further with a range of unique and powerful SPECT and CT options.

Features & Benefits

Man laying on Symbia Intevo Bold scanner bed

More clarity for more patients

We re-engineered SPECT/CT bone imaging to use CT as the frame-of-reference during image reconstruction. The higher image resolution achieved from xSPECT Bone™ technology enables you to better localize and characterize disease for a more accurate representation of each patient’s condition.

As patient populations continue to age, the growing presence of metal implants and pacemakers adds complexity to imaging. iMAR, our CT metal-artifact-reduction technique, helps improve both CT and SPECT attenuation correction in these cases.² xSPECT Bone and iMAR can easily be combined for even greater image clarity.

CT capability

HD detectors

Collimators

Patient-centric design

xSPECT technology

IQ•SPECT

Clinical Use

^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

A 71-year-old male with severe left hip pain during motion underwent a ^99mTc MDP bone SPECT/CT of the pelvis and lumbar spine. xSPECT Bone sharply delineates increased uptake in left acetabulum corresponding to irregular articular surface, peri-articular sclerosis, and narrowing of joint space seen on CT.

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Reducing metal artifacts with iMAR may lead to more accurate quantification

Iterative metal artifact reduction (iMAR) results in the resolution of the vast majority of artifacts associated with dental implants in this head and neck case, which can result in more accurate assessment of functional activity.

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xSPECT Quant enables quantification of tracer uptake to support therapy response assessment

A 22-hour post-injection SPECT/CT scan using xSPECT Quant™ showed heterogeneous tracer uptake in the known primary tumor of the pancreas. xSPECT Quant enables quantification of uptake, which allows dosimetric estimation and assessment of therapeutic response. The use of SAFIRE helped to significantly reduce the noise in the CT image.

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^{Data courtesy of University Hospital of Würzburg, Würzburg, Germany.}

Quantification of therapeutic dose in metastatic lesions with ¹⁷⁷Lu PSMA

xSPECT Quant allows accurate determination of activity in multiple osseous lesions following therapy with ¹⁷⁷Lu PSMA. xSPECT Quant also enables dosimetry applications in order to achieve the highest possible dose to sites of disease while minimizing toxicity risks.

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^{Data courtesy of University Hospital of Würzburg, Würzburg, Germany.}

xSPECT Quant used in ¹²³I MIBG study to accurately evaluate uptake in suspected pheochromocytoma

xSPECT Quantallows for a more accurate evaluation of radiotracer uptake of a suspicious right adrenal gland lesion. Quantification can be helpful in the initial assessment of disease as well as monitoring the therapeutic response.

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^{Data courtesy of Tift Regional Medical Center, Tifton, Georgia, USA.}

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

xSPECT Bone™ sharply delineates skeletal hypermetabolism in the left facet joints of L3-L5 vertebra adjactent to vertebral stabilization pins reflecting bony remodeling and facet arthropathy, which are secondary to vertebral fixation.

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^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

^99mTc MDP Bone SPECT/CT was performed to evaluate loosening of fixation plate. xSPECT Bone shows sharp delineation of focal increased uptake in the bodies of C6 and C7 around the margin of the anterior fixation plate, which suggests hypermetabolism related to bone stress that is secondary to instability and loosening of the anterior fixation plate and screw.

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^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply defines cervical vertebreal instability

A 15-year-old female involved in sports presented with lower back pain. xSPECT Bone shows sharp delineation of focal increased uptake corresponding to bilateral pars fracture in L4 vertebrae, which are delineated on the CT with higher intensity of uptake in the left side.

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^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

Scanner: Symbia Intevo Bold SPECT/CT

xSPECT Quant enables quantification of tracer uptake to support therapy response assessment

Scanner: Symbia Intevo Bold SPECT/CT

^{Data courtesy of University Hospital of Würzburg, Würzburg, Germany.}

Quantification of therapeutic dose in metastatic lesions with ¹⁷⁷Lu PSMA

Scanner: Symbia Intevo Bold SPECT/CT

^{Data courtesy of University Hospital of Würzburg, Würzburg, Germany.}

xSPECT Quant used in ¹²³I MIBG study to accurately evaluate uptake in suspected pheochromocytoma

Scanner: Symbia Intevo Bold

^{Data courtesy of Tift Regional Medical Center, Tifton, Georgia, USA.}

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

Scanner: Symbia Intevo Bold SPECT/CT

^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

Scanner: Symbia Intevo Bold SPECT/CT

^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply defines cervical vertebreal instability

Scanner: Symbia Intevo Bold

^{Data courtesy of Carilion Roanoke Memorial, Roanoke, VA, USA.}

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

Scanner: Symbia Intevo Bold SPECT/CT

Technical Specifications

Tunnel opening	70 cm
Tunnel length	89 cm

Generator power	50 kW
Rotation time	up to 0.5 s
Tube voltage	80, 110, 130 kv
Iterative reconstruction	SAFIRE^{3, 4}
Metal artifact reduction	iMAR^{2, 4}
Slices	16/32¹

Crystal thickness	3/8” or 5/8”
Detector dimension (FOV)	53.3 x 38.7 cm
Energy range	35-588 keV
System sensitivity (LEHR at 10 cm)	202 cpm/μCi
Acquisition modes	Static, dynamic, gated, SPECT, gated SPECT, dynamic SPECT, whole-body, whole-body SPECT, SPECT/CT, xSPECT
Quantitative accuracy	≤ 5%^{4, 5}

Learn more about Symbia Intevo Bold

Download Symbia Intevo Bold brochure (pdf)

32-slice available with optional IVR.

The amount of metal artifact reduction and corresponding improvement in image quality depends on a number of factors including: composition and size of the metal object, patient size, anatomical location, and clinical practice. It is recommended to perform reconstructions with iMAR enabled in addition to conventional reconstruction without iMAR.

In clinical practice, the use of SAFIRE may reduce CT patient dose depending on the clinical task, patient size, anatomical location, and clinical practice. A consultation with a radiologist and physicist should be made to determine the appropriate dose to obtain diagnostic image quality for the particular clinical task.

Optional.

Accuracy of Bq/ml Quantification in Reference to NIST, Measured Using NEMA NU2-94 Test Phantom for 99mTc with LEHR and 177Lu MELP.

Symbia Intevo BoldMore CT for your SPECT/CT

Features & Benefits

More clarity for more patients

Dose reduction without compromise

The right care at the right time

Clinical Use

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

Reducing metal artifacts with iMAR may lead to more accurate quantification

Reducing image distortion with iMAR may improve accuracy of image interpretation

iMAR helps visualization of anatomical and functional findings in areas impacted by metal artifacts

xSPECT Quant enables quantification of tracer uptake to support therapy response assessment

Quantification of therapeutic dose in metastatic lesions with ¹⁷⁷Lu PSMA

xSPECT Quant used in ¹²³I MIBG study to accurately evaluate uptake in suspected pheochromocytoma

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

xSPECT Bone sharply defines cervical vertebreal instability

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

Reducing metal artifacts with iMAR may lead to more accurate quantification

Reducing image distortion with iMAR may improve accuracy of image interpretation

iMAR helps visualization of anatomical and functional findings in areas impacted by metal artifacts

xSPECT Quant enables quantification of tracer uptake to support therapy response assessment

Quantification of therapeutic dose in metastatic lesions with ¹⁷⁷Lu PSMA

xSPECT Quant used in ¹²³I MIBG study to accurately evaluate uptake in suspected pheochromocytoma

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

xSPECT Bone sharply delineates bony remodeling and facet arthropathy

xSPECT Bone sharply defines cervical vertebreal instability

xSPECT Bone sharply delineates severe osteoarthritis in the left hip joint

Technical Specifications

Learn more about Symbia Intevo Bold

xSPECT Bone

xSPECT Quant

Theranostics for personalized cancer care