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Rethink FFR assessment for every patient – accurately measure pressure differences across a stenosis.

Rethink FFR assessment for every patientAdvanced solutions for Fractional Flow Reserve

Cardiovascular diseases are the number 1 cause of death globally, taking an estimated 17.9 million lives each year¹⁾ – 52.5% of which are attributed to coronary heart disease.²⁾ Consequently, related symptoms are taken very seriously: In patients with suspected coronary heart disease, the presence of a stenosis has to be verified, its extent assessed, and the need for revascularization determined.

What do you think?

In how many cases would visual lesion assessment have resulted in a wrong stenting decision?

17.4%

30.7%

43.9%

Make confident decisions when assessing FFR

Accurately measure pressure differences across a stenosis, confidently assess its hemodynamic significance, and make confident decisions for all patients. From catheter-based Fractional Flow Reserve (FFR) assessment to image-based Angio-FFR³⁾ and noninvasive CT FFR: Our portfolio has the right solution for every patient with coronary artery disease. Because as your partner for FFR, we are committed to supporting you in making competent decisions and improving patient outcomes by expanding precision medicine.

Discover our solutions for FFR assessment

: Gold standard: wire-based FFR and non-hyperemic pressure ratios
In patients with coronary artery disease, it’s critical that the hemodynamic relevance of a stenosis is assessed correctly. Catheter-based Fractional Flow Reserve (FFR) assessment is considered the gold standard by international guidelines. Our hemodynamic recording system Sensis Vibe smoothly integrates FFR measurement for an optimal workflow.
Benefits:
Vendor-independent FFR measurement with Sensis Vibe
Can also display non-hyperemic indices, e.g. DFR^TM powered by Boston Scientific
: Less invasive: angio-derived FFR
Pressure wires and hyperemic stimuli can cause patient discomfort, are cost- and time-consuming – and they can’t be used in all patients with a coronary stenosis. Angio-derived FFR is a less invasive option: A software algorithm calculates the Fractional Flow Reserve (FFR) value based on images delivered by our angio systems. This means shorter, less stressful examinations and less dose for you and your patients.
Benefits:
No additional interventional risks for patients*
Fast workflow and less material needed
Patient is already on the table if a stent needs to be placed
_{* Cases which can be assessed with vFFR are stable coronary syndrome and non-ST elevation acute coronary syndrome.}
: Noninvasive: CT-based FFR
Can diagnostics be eased for patients with a suspected coronary stenosis but no acute symptoms? A gentle alternative to the gold standard for Fractional Flow Reserve (FFR) assessment is CT-FFR: Using high-quality images from our Dual Source CT scanners, a software creates an arterial 3D model to simulate the blood flow – so you can determine the presence and functional significance of a coronary stenosis without an invasive procedure
Benefits:
No interventional risks for patients
Fewer unnecessary invasive procedures
Opportunity to reduce overall costs to healthcare system by 26%

View clinical cases of FFR assessments

Diastolic pressure ratio (dPR) case: Non-hyperemic pressure ratio with Sensis Vibe

Fractional Flow Reserve (FFR) case: Hyperemic pressure ratio with Sensis Vibe

Patient history:

69-year-old patient with symptoms of angina pectoris
History of smoking (30 packs/year)

DFR measurement was performed in the RCA (DFR = 0.83)⁴⁾

Learn about scientific evidence for angio-derived FFR

Find out more about the current literature and proven facts regarding angio-derived FFR.

FFR assessment: literature for Angio-FFR

Discover our offering for FFR assessments

Do you want to perform catheter-based FFR, angio-derived FFR, or CT FFR? Our portfolio includes everything you need to accurately measure and assess pressure differences across a stenosis.

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Learn more about our Artis family for interventional imaging

Angiography

Find out how Sensis Vibe amplifies your productivity

Sensis Vibe

Discover our solution for angio-derived FFR assessment

vFFR

Find out what our Dual Source CT scanners have to offer

CT scanners

Discover how you can measure FFR noninvasively

HeartFlow FFR_CT

Services & Support

Education & Training

1) https://www.who.int/health-topics/cardiovascular-diseases/#tab=tab_1

2) https://www.who.int/gho/mortality_burden_disease/causes_death/top_10/en/

https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death

3) Cases which can be evaluated with angio-derived FFR are stable coronary syndrome and non-ST elevation acute coronary syndrome.

4) Not commercially available in all countries.

5) Compared with usual care testing for patients with suspected CAD. Douglas PS et al. 1-Year Outcomes of FFRCT-Guided Care in Patients with Suspected Coronary Artery Disease. J Am Coll Cardiol. 2016;68(5):435-45.

6) Kornowski, R. et al. (2018): Online Angiography Image-Based FFR Assessment During Coronary Catheterization: A Single-Center Study, J Invasive Cardiol., 30(6), pp. 224-229, URL: https://www.ncbi.nlm.nih.gov/pubmed/29543186.

7) Kornowski, R. et al. (2016): Fractional Flow Reserve Derived From Routine Coronary Angiograms, JACC, 68(20), pp. 2235-2237, URL: https://www.sciencedirect.com/science/article/pii/S0735109716353086.

8) Westra, J. et al. (2018): Diagnostic Performance of In Procedure Angiography Derived Quantitative Flow Reserve Compared to Pressure Derived Fractional Flow Reserve: The FAVOR II Europe Japan Study, JAHA, 7(14), p. e009603, URL: https://www.ahajournals.org/doi/10.1161/JAHA.118.009603.

9) Westra, J et al. (2018): Evaluation of Coronary Artery Stenosis by Quantitative Flow Ratio During Invasive Coronary Angiography. The WIFI II Study (Wire-Free Functional Imaging II), Circ Cardiovasc Imaging, 11(3), pp. e007107, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895131/pdf/hci-11-e007107.pdf.

10) Masdjedi, K. et al. (2019): Validation of 3-Dimensional Quantitative Coronary Angiography based software to calculate Fractional Flow Reserve: Fast Assessment of STenosis severity (FAST)-study, EuroIntervention, URL: https://www.ncbi.nlm.nih.gov/pubmed/31085504.

11) Daemen, J. et al. (2019): 100.54 Extended Validation of Novel 3-Dimensional Quantitative Coronary Angiography (3D-QCA) Based Software to Calculate Vessel Fractional Flow Reserve vFFR): The Fast Extend Study, JACC: Cardiovascular Interventions, 12(4), URL: http://interventions.onlinejacc.org/content/12/4_Supplement/S17.1.

12) Tomaniak, M. et al. (2019): TCT-331 Correlation Between 3D-QCA–Based FFR and Quantitative Lumen Assessment by IVUS for Left Main Coronary Stenoses: The FAST Left Main Study, JACC, 74(13), URL: http://www.onlinejacc.org/content/74/13_Supplement/B329.

13) Masdjedi, K. et al. (2018): Validation of novel 3-Dimensional Quantitative Coronary Angiography based software to calculate Vessel Fractional Flow Reserve (vFFR) post stenting: Fast Assessment of STenosis severity POST stenting, The FAST POST-study, presented at: TCT 2018, San Diego, CA.

14) Masdjedi, K. et al. (2019): TCT-110 The Prognostic Value of Angiography-Based Vessel-FFR After Successful Percutaneous Coronary Intervention: The FAST Outcome Study, JACC, 74(13), URL: http://www.onlinejacc.org/content/74/13_Supplement/B110.

Rethink FFR assessment for every patientAdvanced solutions for Fractional Flow Reserve

What do you think?

Make confident decisions when assessing FFR

Discover our solutions for FFR assessment

Gold standard: wire-based FFR and non-hyperemic pressure ratios

Less invasive: angio-derived FFR

Noninvasive: CT-based FFR

View clinical cases of FFR assessments

Benefit of including HeartFlow FFR_CT Analysis in workup of patients with suspected coronary artery disease

Fractional Flow Reserve (FFR) case: Hyperemic pressure ratio with Sensis Vibe

Diastolic hyperemia-Free Ratio case: DFR^TM is Sensis Vibe new non-hyperemic calculation algorithm powered by Boston Scientific

67-year old male, BMI of 37

67-year old male, BMI of 37

67-year old male, BMI of 37

Benefit of including HeartFlow FFR_CT Analysis in workup of patients with suspected coronary artery disease

Benefit of including HeartFlow FFR_CT Analysis in workup of patients with suspected coronary artery disease

Fractional Flow Reserve (FFR) case: Hyperemic pressure ratio with Sensis Vibe

Diastolic hyperemia-Free Ratio case: DFR^TM is Sensis Vibe new non-hyperemic calculation algorithm powered by Boston Scientific

67-year old male, BMI of 37

67-year old male, BMI of 37

67-year old male, BMI of 37

Benefit of including HeartFlow FFR_CT Analysis in workup of patients with suspected coronary artery disease

Benefit of including HeartFlow FFR_CT Analysis in workup of patients with suspected coronary artery disease

Learn about scientific evidence for angio-derived FFR

Discover our offering for FFR assessments

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