Epidemiology
Prevalence:
- Most common medical pathology of pregnancy
- 2-8% of pregnancies, depending on region
- U.S. prevalence = 3.4%
- Worldwide prevalence = 4.6%
- 0.3% prevalence <34 weeks
- 2.7% prevalence >34 weeks
- ~25% PE → PE with severe features
Demographics:
- Highest incidence in low-income countries
- Risk of developing PE is 7x greater in developing countries
- Most common in first-time pregnancies
- ~80% develop between 37-40 weeks and are uneventful
- 40% accounted for by women with overweight or obesity before conception
Atellica® IM sFlt-1 and PlGF Performance Characteristics
Reproductive Care for a Lifetime
Reproductive endocrinology covers a wide range of endocrine disorders related to the reproductive system in both males and females, including puberty and menstrual cycles, infertility, pregnancy, and menopause. As a longstanding leader in reproductive endocrinology, Siemens Healthineers offers a broad range of systems and assays to address the various clinical needs in reproductive health.
“We evaluated the analytical performance of Siemens Healthineers ADVIA Centaur PlGF and sFlt-1 assays (5-days precision study, 2 runs per day, 5 replicates each run) and we were pleased with the results that demonstrated robust precision. Also, there was a close alignment between the methods when compared to commercially available assays. The PlGF and sFlt-1 biomarkers address the unmet need for early detection of preeclampsia and improve patient outcomes.”
Dr. P. Apostolakopoulos
REA Maternity Hospital
Athens, Greece
