QISSA disruptive leap in non-contrast MR Angiography

Planning and execution of CE-MRA requires a high degree of expertise to prevent venous inflow and other artifacts, caused by suboptimal timing of contrast media injection, for example.

With Set-n-go implementation, "QISS provides an easy-to-handle approach for imaging peripheral arteries with little requirements for further adjustments".¹ Additionally, QISS² offers the potential to save operational costs of up to $180 / patient by omitting disposables, contrast agent and lab tests (GFR).³

The software package for non-contrast enhanced peripheral MR Angiography is based on quiescent interval single-shot imaging.

• ECG triggered
• Robust, 2D non-subtractive technology
• Set-n-go implementation (Dot software add-in) for easy application
• Export all images in one series (Combined View, CT-like)

About 347 million people worldwide have diabetes.¹ In many cases this leads to perihperal artery disease.

"The high prevalance of chronic renal impairment in diabetic patients with PAD and the need for high doses of gadolinium based contrast agents place them at risk for nephrogenic system fibrosis."²

QISS³ provides an accurate non-contrast alternative to CE-MRA for demonstrating clinically significant arterial disease in patients where contrast agents are contraindicated.^2,4 Enhance clinical capabilities with access to latest clinical standards of care and improve patient safety with the reduced need for CE-MRA.

"QISS MRA should become the non-contrast MRA technique of choice in patients with renal dysfunction."⁵

Maria Carr, Research Technologist
Northwestern University Feinberg School of Medicine
Chicago, US

High Acceleration Quiescent-Interval Single Shot Magnetic Resonance Angiography at 1.5 and 3T

Non-Contrast-Enhanced ECG-Gated Quiescent Interval Single Shot MR Angiography of the Lower Extremities at 3 Tesla: a Case Report

Quiescent-Intervall Single-Shot Magnetic Resonance Angiography

QISS Non-Contrast MR Angiography: A study of Three Cases with Peripheral Vascular Disease

Peripheral arterial disease in patients with diabetes.

Quiescent-Interval Single-Shot Unenhanced Magnetic Resonance Angiography of Peripheral Vascular Disease: Technical Considerations and Clinical Feasibility

Peripheral arterial disease in a symptomatic diabetic population: prospective comparison of rapid unenhanced MR angiography (MRA) with contrast-enhanced MRA.

Evaluation of peripheral arterial disease with nonenhanced quiescent-interval single-shot MR angiography.

Nonenhanced ECG-gated quiescent-interval single-shot MRA (QISS-MRA) of the lower extremities: comparison with contrast-enhanced MRA.

Comparison of quiescent inflow single-shot and native space for nonenhanced peripheral MR angiography.

Nonenhanced peripheral MR-angiography (MRA) at 3 Tesla: evaluation of quiescent-interval single-shot MRA in patients undergoing digital subtraction angiography.

Evaluating Peripheral Arterial Disease With Unenhanced Quiescent-Interval Single-Shot MR Angiography at 3T

Nonenhanced ECG-Gated Quiescent-Interval Single Shot MRA: Image Quality and Stenosis Assessment at 3 Tesla Compared With Contrast-Enhanced MRA and Digital Subtraction Angiography

ECG-gated quiescent-interval single-shot MR angiography of the lower extremities: initial experience at 3 T.

Non-contrast-enhanced MR angiography at 3 Tesla in patients with advanced peripheral arterial occlusive disease.

Sequence comparison for non-enhanced MRA of the lower extremity arteries at 7 Tesla