Siemens Healthineers nuclear medicine head scan using SAFIRE.

SAFIRESinogram affirmed iterative reconstruction

SAFIRE¹ is a unique CT iterative reconstruction algorithm that uniquely allows for up to 60% lower radiation dose in your CT examinations without compromising image quality.

Features & Benefits

Recognized as a strong iterative reconstruction algorithm²
Significant noise reduction² while maintaining image quality and detail visualization
Low-dose procedures may contribute to an increase in patient referrals, along with patient satisfaction
Designed for simple implementation and easy use

Symbia Intevo Bold scan of the torso using SAFIRE. — Data courtesy of University Hospital of Würzburg, Würzburg, Germany.

Reduce image noise

In this case, SAFIRE helped to significantly reduce the noise in the CT image while using a low-dose protocol. This study was performed on a Symbia Intevo Bold™ SPECT/CT with 42 mAs at 110 kV, resulting in a DLP of 116 mGy*cm.

Biograph Horizon lung scan using SAFIRE. — Data courtesy of Praxis für Fusionierte Bildgebung, Halle (Saale), Germany.

Improve image quality

In this case, SAFIRE allows for excellent CT image quality with oral and IV contrast medium, supporting the staging of adenocarcinoma. The study was performed on a Biograph™ Horizon PET/CT with a 1 minute per bed position and CT scan parameters of 60 ref mAs at 130kV.

Acquire images at lower dose¹

With SAFIRE, excellent co-registered CT images obtained at a low dose (130kV / 61 ref mAs) allowed for the characterization and delineation of a sub-centimeter lung lesion.

Technical Specifications

General Requirements

System

Biograph Vision™³ PET/CT
Biograph mCT PET/CT
Biograph Horizon PET/CT
Symbia Intevo Bold™ SPECT/CT

Minimum Software Version

Symbia Intevo Bold: MI SPECT VB20
Biograph Horizon: PETsyngo VJ10
Biograph mCT: PETsyngo VG50
Biograph mCT Flow: PETsyngo VG50
Biograph Vision: PETsyngo VG75

Other

Please Note: Additional technical pre-requisites may apply. Upon receiving your request, your local Siemens Healthineers representative will clarify whether your system meets the requirements.

In clinical practice, the use of SAFIRE may reduce CT patient dose depending on the clinical task, patient size, anatomical location, and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose to obtain diagnostic image quality for the particular clinical task.

Jensen K, Martinsen AC, Tingberg A, Aaløkken TM, Fosse E. Comparing five different iterative reconstruction algorithms for computer tomography in an ROC study. Eur Radiol. 2014 Dec;24(12):2989-3002.

Biograph Vision is not commercially available in all countries. Due to regulatory reasons, its future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.

Header images data courtesy of Praxis für Fusionierte Bildgebung, Halle (Saale), Germany