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ADVIA Centaur XPT Immunoassay System

ADVIA Centaur XPT Immunoassay SystemThe Formula for the Future. Today.

Designed with one of the most advanced software packages on the market, the ADVIA Centaur^® XPT System is among the highest-throughput systems available. The ADVIA Centaur XPT System delivers the results that clinicians depend upon for accurate diagnoses and better patient care—and does so predictably and consistently.
Siemens unites innovative workflow solutions with clinical excellence in the ADVIA Centaur XPT System, leading to greater laboratory productivity to stay ahead of increasing workload demands.

Simplified operation enhances lab efficiency.
Cutting-edge immunoassay testing supports clinicians in the screening, diagnosis, and monitoring of the most complex diseases.
Powerful automation and software streamline and accelerate your workflow.

ADVIA Centaur XPT Immunoassay System

Features & Benefits

Simplified, continuous operation

Intuitive, icon-driven user interface for simplified training and operation
On-the-fly loading and unloading of samples, reagents, and supplies
2D bar-code scanner uploads test definitions with one easy scan, saving valuable time
Automated daily maintenance and no monthly cleaning procedures
No daily startup procedure
Status light displays system alerts visible from anywhere in the laboratory

Accurate, timely results

Comprehensive menu supports over 70 tests*
Versatile, advanced AE technology, with over 40 active patents, enables continual introduction of new and innovative assays
Up to 240 tests per hour for fast turnaround, even during peak workload times
STAT port allows priority sampling at any time, even when connected to automation
Highly stable, ready-to-use reagents are used on all ADVIA Centaur systems
Disposable sample tips ensure no sample-to-sample carryover
Automated clot management virtually eliminates operator intervention
SMART algorithm software automates repeat and confirmatory testing of reactive samples

Powerful, seamless connectivity

Designed for automation; requires no additional robotics
Point-in-space technology enables direct-from-track sampling
STAT samples can be front-loaded at any time for immediate sampling, driving rapid turnaround time (TAT)
Direct connectivity to Siemens Automation Solutions, the CentraLink™ Data Management System, and Siemens Remote Service (SRS) , enabling laboratories to adapt and grow as their workloads demand

Assays

Download assay menu (pdf) 0.32 MB

Anemia
Active B12
Ferritin
Folate
RBC Folate
Vitamin B12

Autoimmune
Anti-CCP

Bone Metabolism
Intact PTH
Vitamin D Total

Cardiac
BNP
CKMB
High-Sensitivity Troponin I (TNIH)
Myoglobin
TnI-Ultra™

Diabetes
C-Peptide
Insulin

Liver Disease – NASH
ELF™ [Enhanced Liver Fibrosis]

Hepatitis
Anti-HBs2
HAV IgM
HAV Total
HBc IgM
HBc Total
HBe Ag
HBs Ag Confirmatory
HBs AgII
HCV^***

HIV
HIV 1/O/2 Enhanced (EHIV)^§
HIV Combo^§

Immunosuppressant Drugs
Cyclosporine
Everolimus^**
Tacrolimus^**

Inflammation
IgE, Total

Metabolic
Cortisol
Homocysteine

Oncology
AFP
BR 27.29
CA 125II^‡
CA 15-3
CA 19-9
Calcitonin
CEA
Complexed PSA
PSA
Serum HER-2/neu

Reproductive Endocrinology
AFP
Anti-Müllerian Hormone^**
DHEAS
Enhanced Estradiol
Free βhCG^‡‡
FSH
hCG
LH
PAPP-A^‡‡
PlGF^**
Progesterone
Prolactin
sFLT-1^**
SHBG
Testosterone II

Special ID
EBV-EBNA IgG_**
EBV-VCA IgG^**
EBV-VCA IgM^**
Syphilis
Zika IgM^††

Therapeutic Drug Monitoring (TDM)
Carbamazepine
Digitoxin
Digoxin
Gentamicin
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin

Thyroid
Anti-TG
Anti-TPO
Free T3
Free T4
T Uptake
Total T3
Total T4
TSH3-Ultra
TSH

ToRCH
CMV IgG
CMV IgM^**
Herpes-1 IgG
Herpes-2 IgG
Rubella IgG
Rubella IgM
Toxoplasma IgG
Toxoplasma IgM

Technical Specifications

Download ADVIA Centaur XPT System Technical Specifications

Product Specifications
System Description	Random-access immunoassay system
Test Throughput	Up to 240 tests per hour
Time to First Result	18 minutes; results every 15 seconds thereafter, assay dependent
Assays Onboard	30 assays
Disease-State Assay Groups	Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, Immunosuppressant Drugs, Metabolic, Oncology, Reproductive Endocrinology, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH
Continuous Operation	Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste.
Sample Handling
Sample Tubes	3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes
Sample Input	Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading
Validated Sample Types	Serum, plasma, urine (assay-dependent)
Sample Volume per Test	10–200 μL, assay-dependent
Sample Integrity Control	Pressure transducer technology with clot detection, flagging, and management; short-sample detection
STAT Handling	Dedicated STAT port accepts samples any time; STAT samples are processed with priority
Auto-repeat	User-definable
Sample Dilution	Automatic dilution varies by assay, up to 1:2500
Auto-reflex Testing	Automatic ability to perform additional tests based on results of first test
Sample Pipette Tips	840 disposable sample tip capacity
Sample Carryover Prevention	Disposable pipette tips ensure zero sample carryover
Bar Codes
Sample Bar Codes	Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)
Reaction Area
Reaction Cuvettes	Capacity of 1000 optical-grade plastic cuvettes
Reaction Bath	Air bath, 37°C
Assay Result Calculations	SMART algorithm software repeats and confirms reactive testing; results available as completed
Assay Technology	Chemiluminescence using Advanced Acridinium Ester
Reagent Handling
Reagent Tray	30-position reagent tray refrigerated between 4 and 10°C (39–50°F)
Reagent Capacity Onboard	30 assays
Reagent Containers	ADVIA Centaur^® ReadyPack^® (various pack sizes available)
Reagent Integrity Control	Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging
Onboard Stability	28 days (average)
Reagent Mixing	ADVIA Centaur ReadyPacks automatically rocked onboard
Ancillary Reagents	25-position ancillary reagent tray cooled 4–8°C (39–46°F)
Calibration/QC
Auto-calibration/Auto-QC	Available automatic QC ordering by test, control, date, and time
QC Data	Advanced QC package includes Levey-Jennings plots and Westgard rules
User Interface/Data Management
Monitor	22-inch diagonal high-resolution LCD touchscreen with adjustable height
Operating System	Microsoft^® Windows^® 7
System Documentation	Operator manual, quickstart guide, and context-sensitive online help
Data Storage	1,000,000 test/QC results; 500,000 can be historical; can archive to removable media
Onboard Maintenance Logs	Yes
Host Interface	RS232C bidirectional and host query; Ethernet connection available
Host Query	Yes
Remote Access & Service	1000Base-T Ethernet port for remote access and modem for Siemens Remote Service
Removable Media
Removable Media	CD, DVD, or USB
General Specifications
Power Requirements	200-240 V at 50/60 Hz; 1.2 kW maximum
Maximum Water Consumption	2.5 liters (0.6 gallons) per hour
Drain Requirements	Minimum of 2.5 liters (0.6 gallons) per hour
Dimensions	With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in. Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in.
Weight	585 kg (1289 lb)
Compliance	Complies with international environmental, health, and safety standards
Noise Emission	65 dB maximum
Processing Heat Output	5100 BTU/hour
Ambient Temperature	18–30°C (64–86°F)
Ambient Humidity	20–80% noncondensing
Floor Load-Bearing Requirement	412 kg/m² (84 lb/ft²)

Services & Support

Education & Training

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*Assay availability varies

** Under development. Not available for sale.

† Not available for sale in the U.S.

‡ CA 125II is a trademark of Fujirebio Diagnostics, Inc.

§ Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.

*** For outside of the U.S. only, assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.

†† The ADVIA Centaur Zika Test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. This test has been authorized only for the diagnosis for Zika virus infection and not for any other viruses or pathogens. This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of in vitro diagnostic tests for detection of Zika virus and/or diagnosis of Zika virus infection under section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner

‡‡ For Research Use Only in the U.S. Not for use in clinical or diagnostic procedures in the U.S.